North Carolina

Dogs for Adoption in Mebane, NC: 20 Dogs Looking for a Home

Dogs up for adoption near Mebane, NC

372 dogs and puppies are waiting for homes at 17 rescues and shelters within 50 miles of Mebane. Here are the 20 nearest, each with photos, their story and how to reach the rescue looking after them.

Of the dogs up for adoption within 50 miles of Mebane, 136 puppies, 83 young dogs, 131 adults and 17 seniors. The breeds you'll see most are Labrador Retriever, Terrier and American Staffordshire Terrier, along with plenty of one-of-a-kind mixes.

1. Biscuit

Adult (1 year) · Male · Shih Tzu (long coat) · 23 mi from Mebane

Biscuit is a resilient, affectionate small-breed rescue dog who is fully vetted and ready to transition into a forever home that can accommodate his specific care, space, and family needs. After a rough start on the side of a busy road, he has successfully adjusted to crate training, car rides, and coexisting with other animals.

Quick Profile

· Health Status: Neutered, microchipped, fully vaccinated, and current on all preventative medications.

· Coat Care: Non-shedding; requires professional grooming every 6 to 8 weeks.

Read more about Biscuit

· Social Compatibility: Friendly with cats and other dogs; specifically desires a small-breed female canine companion.

Ideal Home Requirements

· Family Dynamic: Adults or families with children aged 10 and older; excellent fit for work-from-home professionals.

· Sleeping Arrangement: Allowed to sleep in the bed with his owners to satisfy his love for cuddling.

· Property Features: A securely fenced yard to support his ongoing house training and provide safe, immediate outdoor access.

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Biscuit fromChatham Animal Rescue & EducationPittsboro, NC · listed Nov 1

3. Winnie

Adult (2 years) · Female · Wheaten Terrier / Schnauzer (long coat) · 23 mi from Mebane

Winnie has no idea that she’s special — but she is. To her, she’s just a happy, playful dog living her best life. Winnie was born with a cerebellum that didn’t fully develop in utero, a condition believed to be cerebellar hypoplasia. This affects her balance and gives her a uniquely wobbly, slightly unsteady way of walking. It doesn’t cause her pain, and it certainly doesn’t dim her spirit. Winnie is, without question, the happiest dog her foster family has ever met.

Read more about Winnie

For the most part, Winnie is a normal dog: she plays, she explores, she loves her people, and she radiates joy. She simply needs a family willing to love and care for her exactly as she is — wobbles and all.

Winnie would thrive in a home with another gentle dog her size or larger who can play with her, keep her company, and help her feel secure. She adores canine friends and blossoms with companionship.

Winnie is up to date on all vaccines and preventatives, has been spayed, and is microchipped. Any children in the home should be at least 8 years of age. She also requires a fenced in yard, physical fencing attached to the home

Winnie doesn’t know she’s different — she only knows she’s loved. If you’re looking for a dog who will brighten your home with pure happiness and endless heart, Winnie may be the perfect match.

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
  • Special needs
Adopt Winnie fromChatham Animal Rescue & EducationPittsboro, NC · listed Oct 24

4. Ernest

Adult (3 years) · Male · Terrier / Dachshund / Mixed (medium coat) · 23 mi from Mebane

Ernest is an approximately 3‑year‑old sweetheart with a calm, affectionate nature and a touch of playful confidence. He has an absolutely adorable little underbite that makes him look like he’s smiling all the time, and it suits his gentle, goofy charm perfectly. He can be a bit bossy with dogs who don’t like to listen, but in a home with well‑mannered canine companions, he settles in beautifully.

Read more about Ernest

When Ernest first arrived in foster care, he wanted to be close to his people without actually touching. With patience and reassurance, he has blossomed into a cuddler. He’ll happily stretch out on your chest for a bit before sliding over to relax right beside you. His foster family has loved watching him learn that affection is safe and comforting.

Ernest enjoys playing with the other dogs in his foster home, and he will do best in a home with at least one friendly canine companion. He thrives with dogs who are kind, confident, and not easily pushed around.

Ernest is up to date on all vaccines and preventatives, has been microchipped, and is neutered. Because of his coat type, he will require regular professional grooming, and his ideal family will have experience with maintaining a dog who needs consistent coat care.

Ernest is a gentle, loving boy who’s ready for a family that will continue helping him grow in confidence and enjoy the comfort of companionship. If you’re looking for a sweet dog with a tender heart, a playful spirit, and a smile that never quits, Ernest may be the perfect addition to your home.

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Ernest fromChatham Animal Rescue & EducationPittsboro, NC · listed Oct 24

5. Addie

Adult (3 years) · Female · Terrier / Poodle (Miniature) / Mixed (medium coat) · 23 mi from Mebane

Meet Addie!

She is
a fun, playful, and incredibly dedicated companion who is looking for a family to love her. Found as a stray with very little known about her background, it was obvious she needed immediate medical attention when she entered rescue.
She suffered from a large inguinal hernia with part of her intestines trapped. Luckily, Addie received the life-saving surgery she needed and is now completely healed, healthy, and ready for a long, happy life with her forever humans!

Medical Status

Fully Vetted:
Addie is
spayed, microchipped, and fully vaccinated
.

Read more about Addie

Health Update:
Her
inguinal hernia repair
has given her a brand-new lease on life, and she has no remaining restrictions from her recovery.

Her Ideal Home

Human Companionship:
Thrives when she isn't left alone for long hours. She would make the
absolute best work-from-home coworker ever.

Snuggle Requirements:
Daily
lap time is required
, and nighttime snuggles rank at the very top of her "must-haves" list.

Children:
Best suited for families where all children are
10 years of age or older.

Yard:
Preference will be given to homes with a
fenced-in yard (structured fencing only)
so she can safely enjoy fetch and outdoor exploration.

Other Pets:
Social and sweet, she
makes fast friends with both dogs and cats
and enjoys their company.

Activity & Training:
Loves to race around the yard and enjoy daily strolls. She is still learning not to pull on her leash, so she will need a family willing to help her practice her leash manners.

Addie's ultimate goal is to find humans who will truly include her in all that life has to offer. If your home sounds like the perfect match for this resilient girl, please apply today!

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Addie fromChatham Animal Rescue & EducationPittsboro, NC · listed Oct 15

6. Pebbles

Young (5 months 6 days) · Female · Beagle / Hound / Mixed (short coat) · 23 mi from Mebane

Pebbles is a young, spirited beagle girl who doesn’t let anything slow her down — not even the fact that she’s missing her right rear foot. Her veterinarian has confirmed she’s healthy and thriving; she simply needs her leg wrapped or covered with a bootie during play and outdoor time to keep it protected. Pebbles doesn’t mind one bit. She’s far too busy exploring, learning, and having fun.

This sharp little lady loves to play and has a confident, sometimes bossy streak. Because she’s a beagle with a nose that can lead her into mischief, Pebbles requires a securely fenced yard attached to the home to keep her safe during outdoor time.

Read more about Pebbles

Due to her personality, Pebbles also needs a home with one docile, friendly male dog who won’t challenge her.

Pebbles is up to date on all vaccines and preventatives, has been microchipped, and will be spayed when age‑appropriate.

Pebbles is full of potential and joy — she just needs the right home to help her shine. If you’re looking for a clever, lively companion with a whole lot of heart, Pebbles may be your perfect match.

  • Special needs
Adopt Pebbles fromChatham Animal Rescue & EducationPittsboro, NC · listed Oct 10

7. Nessa

Puppy (5 months 18 days) · Female · Labrador Retriever / Giant Schnauzer / Mixed (medium coat) · 23 mi from Mebane

Meet Nessa! We think she could be a mix of Lab or Great Dane and some sort of wiry-haired terrier, but whatever she is, her paws tell us she's going to be a great big beautiful girl. Good thing she's such a sweetheart who loves to learn. Nessa requests your treats and chin scratches and she can provide giant cuddles as payment!

Read more about Nessa

In her foster home, she's house trained, knows some basic commands like sit/down, and takes treats gently. She's learning to walk politely on a leash and sleeps well in her crate at night. She loves to chase the ball, but she hasn't yet gotten the hang of bringing it back. During the day, she's still learning that her crate can be her safe place because she loves to be with people. Having another dog in the home could help her feel more confident when her people leave the house.

Nessa is current on vaccines and microchipped.

  • Good with dogs
  • House-trained
Adopt Nessa fromChatham Animal Rescue & EducationPittsboro, NC · listed Sep 28

8. Hank

Adult (5 years 2 months) · Male · Beagle / Basset Hound / Mixed (short coat) · 23 mi from Mebane

Hank is a 5‑year‑old beagle mix with a heart as sweet as they come. Despite a very difficult start to life, he has held onto his gentle nature and his love for people. His past left him with permanent scarring from having his mouth cruelly tethered shut, but Hank’s spirit is remarkably intact — he greets kindness with trust, warmth, and quiet gratitude.

Read more about Hank

When he entered rescue, Hank needed extensive dental care and tested positive for heartworm. He is receiving all necessary treatment, and he will complete every step before leaving foster care. Through it all, he has remained patient, affectionate, and eager to be close to the humans who show him compassion.

Hank gets along wonderfully with other dogs and enjoys their company. His calm, friendly demeanor makes him an easy companion, whether he’s relaxing at your feet or exploring the yard with a canine friend.

This brave boy is ready for a home where he can finally experience the safety, comfort, and love he’s always deserved. If you’re looking for a deeply sweet, resilient dog who will reward your kindness with unwavering loyalty, Hank may be the perfect match.

As a beagle, Hank requires a securely fenced yard with physical fencing attached to the home. He has been neutered, microchipped, and is fully vaccinated.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Hank fromChatham Animal Rescue & EducationPittsboro, NC · listed Sep 12

9. Joey

Young (1 year 3 months) · Male · Chihuahua / Pomeranian / Mixed (long coat) · 23 mi from Mebane

Up in the sky! Look! It's a Pomeranian! It's a Chihuahua! It's Joey! Joey is a year old, eight pound, long-haired Chi-pom mix, and his energetic personality matches this medley of furballs.

Joey was found as a stray in a cage with 6 or 7 other similar-looking dogs. He is not used to living indoors with humans, but he is slowly becoming confident. He has learned a lot in the meantime: to settle in his crate, to take walks on a leash, and to play with his toys independently.

Read more about Joey

Joey loves chasing dragonflies and army-crawling in tall grass. He loves sprinting in the yard and chewing on collagen sticks and yak cheese. He especially loves his snuffle mat!
There are a few quirks about Joey that will take patience from his future humans. Although he has learned to toilet outdoors, he hasn’t quite gotten over some handling issues. Fear and excitement cause him to have little accidents. Thankfully, he is very small and has gotten used to wearing a belly band. Joey also needs to be closely watched as he enjoys jumping from high places and will need to be discouraged from parkouring. But hey, that means he might be great for an agility course!

Joey is young and acts like a puppy, so obedience training is a must. He should not be in a home with children younger than 10. He enjoys sprinting outside and would be best in a home with a big, physically-fenced yard.

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Joey fromChatham Animal Rescue & EducationPittsboro, NC · listed Aug 24

10. Etta

Adult (3 years 4 months) · Female · French Bulldog (short coat) · 23 mi from Mebane

Etta only had one reason for being wanted in her previous life- she was a breeder. Unfortunately, producing puppies for profit isn't something that also afforded her the love and care she deserved in her previous life. Etta's ears no longer stand up due to severe untreated infections. Etta chose not to compete with all of the other dogs she lived with for food, so she was underweight when she entered foster care. Despite these conditions, Etta is a total love bug. She deserves the RIGHT family to spend her days with, and that is exactly what she will have.

Read more about Etta

Etta has been spayed, micro chipped, and is up to date on all preventative medications. She also had a soft palate surgery and nasal stenosis, to help her breathe better. She has allergies, so she will require regular visits to the vet to deal with them, as needed. She will need to stay on a fatty acid and joint supplement, and will require special food and daily probiotics- for life. There is no such thing as an inexpensive French Bulldog, so please be sure you not only have the means- but the willingness, to afford her CARE. An experienced dog owner is a must (with an impeccable vet reference), preference will be given to those who are familiar with Brachycephalic breeds and the special care they require.

Etta has occasional zoomies, and she would love another dog to wrestle with (she will adjust her play to the size of her companion), and loves a leisurely early morning walk when the temperature is safe for her to be outside- but otherwise she is a snoring, snorting, flatulence filled- couch potato. She adores her people, so someone who isn't gone for long hours is a plus. When you are gone, she is crate trained and loves a stuffed kong to keep her busy. She is good with cats, but would do best with a dog savvy cat. Etta is a "private pooper", she chooses the outskirts of the yard to potty, so she requires a secure fenced in yard (physical fencing only, please) to keep up her good potty habits. All children in the home should be 10 and over, she gets a bit too excited with wee children.

For the RIGHT home, Etta will be a fabulous addition. She has spent her limited time on this earth giving everything to humans who didn't appreciate her. Now it's Etta's turn to have her needs met. We know her wish list is long, we aren't looking for average- Etta deserves the BEST.

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained

11. Cali

Young (11 months) · Female · Belgian Shepherd Malinois / American Staffordshire Terrier / Mixed (short coat) · 31 mi from Mebane

Meet Cali!
❤️

Sweet, smart, loving, and always ready to make a new friend — that’s Cali!

Cali is the kind of dog who makes it easy to fall in love with her. She absolutely loves people and welcomes new friends with a happy, friendly personality. But what makes Cali really special is her desire to please and her genuine love of being loved.

Read more about Cali

She is housebroken, crate trained, and wonderfully well behaved. Cali is comfortable spending a normal workday in her crate and settles in beautifully, making her a great companion for someone who works outside the home. She is also a relatively quiet girl, so she doesn't need to be the center of attention all the time.

Cali is smart and eager to learn. She has attended training classes with her foster canine brothers and did exceptionally well. She already knows her basic commands and picks up new things quickly. Her foster family has been impressed by how much she wants to please.

She also has a wonderful history with both dogs and young children. When she was first found, Cali lived with two Australian Shepherds and did very well with them. She also spent two months living with children ages 3 and 5 and was terrific with them. She takes everyday noises and activity in stride.

Cali enjoys a good walk and is excellent on leash, but she also loves having a yard where she can explore and enjoy herself. She would be happy in a home with a fenced yard, but she could also do well without one as long as she gets regular walks and exercise.

Cali would be perfectly happy as an only dog, but she really enjoys canine companionship, so she'd also love having a doggy friend. She has not yet been exposed to cats, so that would be something to consider when finding her perfect home.

Most of all, Cali wants a family to love and a family who will love her back. She is affectionate, adaptable, eager to please, and just an all-around wonderful girl. Whether you're looking for a walking buddy, a training partner, a couch companion, or simply a loving member of the family, Cali is ready to be your girl.

Cali is ready to find the people she can love for the rest of her life. Could that be you? ❤️

Some of the information contained in this biography includes approximations based on our expertise and is not guaranteed. Applicants ideally should live no further than one hour from Cary NC as our dogs must be seen by a BFPA veterinarian for all medical care prior to adoptions being finalized. Our foster guardians deliver dogs to their new homes for adoption trials and we do home visits to finalize all adoptions. We therefore prefer applicants that live within an hours drive of Cary NC.

INTERESTED IN MEETING OR ADOPTING Cali from Best Friend Pet Adoption rescue? If so, please fill out our dog adoption application by copying and pasting this link in a new browser window: https://toolkit.rescuegroups.org/of/f?c=WHMSYCNC.

This is always the first step which needs to be completed before meeting any Best Friend Pet Adoption dog.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Cali fromBest Friend Pet AdoptionCary, NC · listed Sep 30

12. Tiki

Puppy (4 months 17 days) · Plott Hound · 31 mi from Mebane

NOTE: Tiki is a courtesy listed dog. Best Friend Pet Adoption is helping to find a home for this handsome dog. Please do not submit an application to Best Friend Pet Adoption. For more information about this dog, please contact winfield.beverley@gmail.com.

Tiki is a world traveler and has frequent flyer miles already! He came all the way from St. Croix with a dream to find his forever family. Could you give this cute guy his dream come true??

Read more about Tiki

Tiki is a fast learner and loves to play with other dogs. He looks forward to seeing his friends at doggie day care. He has been around cats and wants to play with them. Tiki could live with other dogs or could be an only dog.

He can be a bit timid around new people but once he realizes that he is safe, he will be your friend. Very young children tend to make him wary. He would do best with older children. He will cuddle some, but isn’t a lap dog, though he loves to hang out with his people.

He would love a fenced yard but would be fine being on a leash for walks and his potty breaks. Since Tiki can be vocal at times, he would not be suited for apartment living.

Tiki is almost totally house broken when taken out for potty breaks regularly. He is used to being in a puppy pen when he is left alone.

He likes car rides and going places. He is full of energy and likes to play, so would be great for an active home. If you are ready to toss a ball or run around with him, please contact Beverley at winfield.beverley@gmail.com.

DISCLAIMER: We hope you'll consider adopting Tiki. He is a courtesy listed dog. This means that the dog is not a part of or associated with Best Friend Pet Adoption (BFPA). The bio information listed for Tiki was provided by his owner/rescuer and not generated or verified by BFPA. Adoption arrangements will be a private arrangement between you and the owner/rescuer. As with any dog adoption, BFPA encourages potential adopters to gain as much information as possible before adopting. This includes temperament testing and verification of vet records to ensure the dog is in good health, up to date on vaccinations and has been sterilized. For more information about Tiki, please contact winfield.beverley@gmail.com.

  • Good with dogs
  • Good with cats
Adopt Tiki fromBest Friend Pet AdoptionCary, NC · listed Aug 27Courtesy listing: Tiki's family is rehoming them through this rescue.

13. Bruno

Adult (6 years) · Male · Terrier / Mixed (short coat) · 31 mi from Mebane

Meet Bruno! At 6 years old, Bruno has the perfect balance of playful energy and laidback companionship. He's been waiting far too long for his forever family, and everyone who knows him agrees—it's finally his turn. This handsome, happy boy weighs about 65 pounds and has an infectious smile that's impossible to resist.

With one ear standing tall and the other adorably flopped over, Bruno is as unique on the outside as he is on the inside. While he isn't exactly lap dog sized, don't tell him that! He loves being close to his people, soaking up affection, handing out sweet kisses, and claiming his favorite spot right beside you on the couch.

Read more about Bruno

Bruno has settled beautifully into foster care and has shown everyone what makes him such a special companion. He's fully house trained, crate trained, and is perfectly content relaxing in his crate when left home alone. Around the house, he's an easygoing guy who enjoys lounging on the couch, chewing on a frozen treat, or entertaining himself with his toy collection. His absolute favorite? A Lamb Chop stuffie!

Bruno would thrive as the only dog in his home, where he can soak up all the love and attention. While he's not looking for a busy multi-dog household, he has shown that he can enjoy the company of respectful female dogs. He has made several female dog friends and loves having supervised play sessions with them, as long as they respect his pace and personal space. Because of this, we'd be happy to discuss a home with the right easygoing female dog, but Bruno's ideal match is a family where he can be the center of attention.

He enjoys walks and does well on leash, though he's still working on polishing his leash manners when he gets excited. He also loves chasing thrown toys, even if bringing them back is still a work in progress! Due to his size and enthusiastic personality, Bruno would do best in a home with children ages 10 and older. Bruno has spent far too much time waiting for someone to choose him.

At 6 years old, he's past the puppy chaos but still has plenty of life, love, and playful moments to share. He's ready for a family that will appreciate his goofy personality, loyal heart, and love of life's simple pleasures—like couch cuddles, stuffed toys, and spending time with his favorite humans.

DISCLAIMER: We hope you'll consider adopting BRUNO. He is listed as a courtesy. This means that he is not a part of or associated with Best Friend Pet Adoption (BFPA). The bio information listed for BRUNO was provided by individual caregivers and not generated or verified by BFPA. Adoption arrangements will be a private arrangement between you and Underhoundrailroad.org. As with any dog adoption, BFPA encourages potential adopters to gain as much information as possible before adopting. If you have any questions about Bruno, please contact

adoptions@underhoundrailroad.org.

Bruno is currently fostered in South Carolina and can be transported along the East Coast as far north as Maine to his forever family. If you think Bruno could be the missing piece of your family, apply today at https://underhoundrailroad.org/adoption-application/. Bruno's adoption fee has been generously sponsored! If adopted within South Carolina, his adoption fee is just $50. For out-of-state adopters, his fee is $175.

Adopt Bruno fromBest Friend Pet AdoptionCary, NC · listed Jul 20Courtesy listing: Bruno's family is rehoming him through this rescue.

14. Alaska

Puppy (5 months 30 days) · Female · Plott Hound / German Shepherd Dog / Mixed (medium coat) · 31 mi from Mebane

PLEASE NOTE: If you are on PetFinder or other search site, you do NOT need to introduce yourself. All dogs on our website ARE available and require an approved Best Friend Pet Adoption application before you can be considered or meet any of our dogs. The link to our application is in the dogs bio below.
Alaska is the perfect match for anyone seeking a cuddle buddy, a walking partner, or a pup who brings daily laughter. At just five months old, this Plott Hound/German Sheperd mix is blossoming into a wonderful young dog who’s eager to find her forever family. Alaska has that classic puppy curiosity—everything is new, exciting, and worth investigating—and her enthusiasm for everyday moments is guaranteed to brighten your day.

Read more about Alaska

She is crate trained and house broken! She learns new things quickly, and is settling into the rhythms of home life. With her sweet nature, eagerness to learn, and joyful spirit, Alaska is ready to grow into an incredible companion alongside the lucky family who chooses her.
Some of the information contained in this biography includes approximations based on our expertise and is not guaranteed. Applicants must live no further than one hour from Cary NC as our dogs must be seen by a BFPA veterinarian for all medical care prior to adoptions being finalized. Our foster guardians deliver dogs to their new homes for adoption trials and we do home visits to finalize all adoptions. We therefore require applicants to live within an hours drive of Cary NC. INTERESTED IN ADOPTING ALASKA? If so, please fill out our dog adoption application by copying and pasting this link in a new browser window: https://toolkit.rescuegroups.org/of/f?c=WHMSYCNC

Adopt Alaska fromBest Friend Pet AdoptionCary, NC · listed Jun 15

15. Mai Mai

Adult (6 years) · Female · Japanese Chin (long coat) · 31 mi from Mebane

IMPORTANT Hart-2-Heart only posts our dogs on Petfinder and Adopt-A-Pet. Once you contact us directly, we will email you our adoption application. Please do not complete an application on any pet adoption platform, as we only accept applications submitted on the form we provide.

If you are interested in adopting this dog, please contact us at h2hadoptions@gmail.com.

---------

The adoption range for this dog is limited to NC, SC, VA, Northeastern GA, East TN Southern MD, and the DC area.

-----------

Read more about Mai Mai

Mai Mai is a delightful 6-year-old female Japanese Chin weighing 14 pounds. She is a gentle, sweet girl with a charming personality who gets along wonderfully with other dogs.

True to her breed, Mai Mai has some endearing and unique quirks! She does the classic Japanese Chin "chin wave," happily waving her front paws to greet you or get your attention. She is also meticulously tidy and loves to groom herself just like a cat.

Mai Mai is searching for a loving home with a securely fenced yard, as she is not yet leash-trained and needs a safe outdoor space to explore at her own pace. She would thrive in a patient household that can help her continue to build confidence and learn new routines.

If you are looking for a tender, loving companion to add warmth and joy to your home, Mai Mai is ready to win your heart!

Please contact h2hadoptions@gmail.com directly to inquire about adopting Mai Mai. There is an application process and an adoption fee.

WE REQUIRE AN ALL-ADULT HOME WITH A SECURELY FENCED YARD. The secure fence must be attached to the home, 4 feet or higher with gaps with no larger than 2.5 inches. An invisible fence, enclosed patio or terrace without grass, temporary fencing, dog pens or dog lots or community shared fencing (dog park) are NOT considered secure fencing. If your fencing has "puppy pickets" (or is supplemented with garden fencing) it needs to be at least 36 inches high from the ground up AT THE LOWEST POINT. No exceptions.

We are an all-volunteer organization, and in addition to saving dogs, we have other responsibilities, so we appreciate your patience and understanding during this process. Response time can take up to 5 business.

Please inquire only if you are willing to come to Greensboro, NC to meet the dog after we schedule your home visit. We do not ship dogs or put them on transports.

Veterinary Care: All Hart-2-Heart Rescue foster dogs are spayed/neutered, current on heartworm prevention, parvo/distemper, bordetella, and rabies vaccines, and are professionally groomed. As needed, our foster dogs have teeth cleanings, extractions, bloodwork and other diagnostic testing.

Adoption Fee: $650

  • Good with dogs
Adopt Mai Mai fromHart-2-Heart Rescue, Inc.Greensboro, NC · listed Aug 23

16. Chip

Adult (4 years) · Male · Yorkshire Terrier Yorkie / Mixed (long coat) · 31 mi from Mebane

IMPORTANT Hart-2-Heart Rescue, Greensboro, North Carolina only posts our adoptable dogs on Petfinder and Adopt-A-Pet. Once you email us we will email you questions and our adoption application. Please do not complete an application for any of our dogs on a pet adoption platform, as we only accept applications submitted on the application we sent you.

If you are interested in adopting this dog, please contact us at h2hadoptions@gmail.com.

---------

The adoption range for this dog is North Carolina, South Carolina, northeastern GA, east TN, DC area, VA, and southern MD.

-----------

Read more about Chip

Chip is an adorable 4-year-old Yorkie mix weighing 9 pounds. His coarse coat is low maintenance and low to no shed.

Chip is an active, athletic terrier who loves toys and is good at entertaining himself. He would make a great companion for someone who enjoys walking or is interested in clicker training. Like most terriers, he'll bark when there's something worth announcing, and he is undeterred by his tiny size.

Chip is initially unsure when he meets new people, but learned quickly to trust his foster mom and other women. He is slower to trust men, so his adopter will need to be patient and allow him time to adjust at his pace.

Because Chip is quick and can dart through open doors, his new family must be vigilant around exterior doorways.

The ideal home for Chip would be with someone who has experience going slow and moving at Chip’s pace and wants to bond with a dog through training and enrichment activities.
Chip has made great progress with house training in his foster home, and needs a patient person to continue his routine and training.

Chip will do best as an only dog; however, he has learned to co-exist peacefully in his foster home.

Please email h2hadoptions@gmail.com directly. There is an application process and a $500 adoption fee.

WE REQUIRE AN ALL-ADULT HOME WITH A SECURELY FENCED YARD. The secure fence must be attached to the home, 4 feet or higher with gaps with no larger than 1.25 inches. An invisible fence, enclosed patio or terrace without grass, temporary fencing, dog pens or dog lots or community shared fencing (dog park) are NOT considered secure fencing. If your fencing has "puppy pickets" (or is supplemented with garden fencing) it needs to be at least 36 inches high from the ground up AT THE LOWEST POINT. No exceptions.

We are an all-volunteer organization, and in addition to saving dogs, we have other responsibilities, so we appreciate your patience and understanding during this process. Response time can take up to 5 business.

Please inquire only if you are willing to come to Greensboro, NC to meet the dog after we schedule your home visit. We do not ship dogs or put them on transports.

Veterinary Care: All Hart-2-Heart Rescue foster dogs are spayed/neutered, current on heartworm prevention, parvo/distemper, Bordetella, and rabies vaccines, and are professionally groomed. As needed, our foster dogs have teeth cleanings, extractions, bloodwork and other diagnostic testing.

Adoption Fee: $500

Adopt Chip fromHart-2-Heart Rescue, Inc.Greensboro, NC · listed Aug 3

17. Chase

Adult (6 years 2 months) · Male · Yorkshire Terrier Yorkie · 31 mi from Mebane

IMPORTANT NOTE: We ONLY post our dogs on Petfinder and Adopt-A-Pet! If you see Hart-2-Heart dogs on ANY OTHER platform, it is likely a SCAM - DO NOT submit an application on that platform!

-----------

The adoption range for this dog is limited to NC, SC, VA, northern GA, DC area, southern MD and east TN. If you are interested in adopting this dog, you MUST contact h2hadoptions@gmail.com directly. There is an application process and adoption fee.

-----------

Chase is a fun-sized 5lb Yorkie who is 6 years old. He is a great cuddler and the perfect lap buddy.

Read more about Chase

Chase can be shy when you first meet him. He came to us as a breeder-release dog, having never lived in a home as someone’s beloved pet. Many dogs like this have never been on a leash or set foot on grass to potty. Chase was a little reserved in the beginning, but since adjusting to his foster family, he has really come to life.

Chase is smart and curious. He’s always smiling and gets excited when you talk or play chase with him. He loves to play with the other dogs in his foster home. We require his adoptive home to have another small social dog under 12lbs so he can continue to watch and learn from another dog in the home.

Chase is still learning house-training and leash walking, so he will need someone with time and patience to help him be successful. We require an all-adult home with a small, securely fenced yard. The fenced yard is not so he can be left alone, but to help with house-training, since most pups do not want someone hovering over them when trying to potty. Chase is trying to learn how to use stairs, so we prefer a home with limited to no stairs.

There is an application process and adoption fee.

WE REQUIRE AN ALL-ADULT HOME WITH A SECURELY FENCED YARD. The secure fence must be attached to the home, 4 feet or higher with gaps with no larger than 1.5 inches. An invisible fence, enclosed patio or terrace without grass, temporary fencing, dog pens or dog lots or community shared fencing (dog park) are NOT considered secure fencing. If your fencing has "puppy pickets" (or is supplemented with garden fencing) it needs to be at least 36 inches high from the ground up AT THE LOWEST POINT. No exceptions.

We are an all-volunteer organization, and in addition to saving dogs, we have other responsibilities, so we appreciate your patience and understanding during this process. Response time can take up to 5 business.

Please inquire only if you are willing to come to Greensboro, NC to meet the dog after we schedule your home visit. We do not ship dogs or put them on transports.

Veterinary Care: All Hart-2-Heart Rescue foster dogs are spayed/neutered, current on heartworm prevention, parvo/distemper, bordetella, and rabies vaccines, and are professionally groomed. As needed, our foster dogs have teeth cleanings, extractions, bloodwork and other diagnostic testing.

Adoption Fee: $500

  • Good with dogs
Adopt Chase fromHart-2-Heart Rescue, Inc.Greensboro, NC · listed Jun 11

18. Powerade

Young (3 years 9 months) · Male · Labrador Retriever / Mixed (medium coat) · 34 mi from Mebane

Meet Powerade

Powerade is a 3-year-old yellow lab mix with the softest eyes and the sweetest soul. He might start off a little shy, but give him a minute (and maybe a treat), and suddenly you’ve got a full-blown Velcro dog who thinks your personal space is a myth.

Read more about Powerade

Pow may have had a rough start, judging by some of his scars - but he’s well on his way to a happier life! His luck began to change one cold, December day when he ran into the Food Lion on Alamance Church Rd in Greensboro, seeking warmth and help. GCAS Animal Control picked him up and brought him to the shelter, even allowing him to ride shotgun on the way there! After some time at GCAS he began to show signs of stress and was able to go to foster.

While in foster, we’ve learned that this guy is the total package:
- House trained
- Crate trained
- Walks nicely on leash
- Knows “sit” (especially if snacks are involved)
- Treat and toy motivated (fetch = his love language)

Once he warms up, Powerade is goofy, playful, and so affectionate. He loves a good game of fetch just as much as he loves melting into you for snuggles. He will follow you room to room just to make sure he’s not missing out (can we say FOMO?)

Pow does have a couple of endearing quirks:

Occasionally jumps up when he’s excited, but redirects beautifully into a sit

Can be a little “mouthy” in an affectionate, playful way—he uses his mouth to explore the world, and responds well to gentle correction

Powerade would thrive in a home that understands his sensitive side:

Has done well with kids as young as 3, but due to his size and occasional jumping up would likely do best with older kids or adults

No cats or small animals (that retriever instinct is strong)

Could potentially live with another dog with very slow, thoughtful introductions, but may also be happiest as your one-and-only. He has done well with other dogs in public spaces and frequently “buddy walks” with friends in the neighborhood.

Health note: Powerade previously tested heartworm positive while at the shelter, but now has a negative test!

What makes Powerade truly special is his heart. This boy has been through a lot, but you’d never know it by how deeply he loves. He is trusting, loyal, and endlessly affectionate—a certified good boy who just wants someone to belong to.

If you’re looking for a sweet, snuggly shadow with a playful streak and a heart of gold… Powerade might just be your perfect match.

  • Good with dogs
  • House-trained
Adopt Powerade fromTails of the UnwantedGreensboro, NC · listed Sep 21

19. Polly

Adult (4 years 3 months) · Female · Terrier / Mixed (short coat) · 34 mi from Mebane

From Polly’s Foster -

Polly has settled in beautifully and has been an absolute sweetheart! She loves belly rubs and is happiest when she’s curled up or sitting right beside her person. She’s incredibly affectionate and never misses an opportunity to hand out plenty of kisses.

She’s fully crate trained and happily puts herself to bed in her crate each night. Polly has only barked a couple of times over the past week, and both were simply to let us know someone was at the door.

Read more about Polly

She walks nicely on a leash with very little pulling and is highly food and treat motivated, always taking treats gently. She loves her toys, especially a good game of fetch!

Polly already knows several commands, including sit, shake, come, down, kiss, walk, no, and crate.

She would thrive as the only pet in the home. While she is non-reactive to dogs and cats when on a leash, she is not a fan of living with cats. Polly also loves the water! She enjoys swimming and has even gone paddle boating with a previous foster.

Her ideal home would have older children or teenagers and a securely fenced yard where she can run, play, and enjoy life to the fullest.

if you are interested in Polly, please complete an adoption application at lastdaydogs.com

  • House-trained
Adopt Polly fromTails of the UnwantedGreensboro, NC · listed Jul 11

20. Oggie

Young (2 years 1 month) · Male · Labrador Retriever / Boxer / Mixed (medium coat) · 34 mi from Mebane

Meet Oggie!

Applicant:
Oggie

Age:
2 years young

Build:
Big, athletic & professionally clumsy

Special Skills:
Master toy dissector, professional car-ride enthusiast & Olympic-level cuddler!

Oggie is a big, goofy Shepherd/Boxer/Lab mix who earned his name because, well… he’s a little bit of an ogre! But don’t let his size fool you—inside this big body is pure honey-colored sweetness.

Oggie is the
ultimate leaner
. He’ll glue his big body to your legs for chest scratches, then happily plop down for belly rubs. He loves his people, loves attention, and would happily spend his days as your oversized shadow.

Read more about Oggie

And this handsome guy is already a certified good boy! Oggie is
fully house- and crate-trained
and knows his basic commands, including
sit, shake, down and crate
. He’s also a huge fan of car rides and can turn just about any toy into a fun dissection project!

Oggie is a social butterfly and
loves other dogs
. If he spots a potential dog friend, though, his recall can mysteriously disappear! He can also get a little
mouthy when he’s excited
, so because he is a strong, enthusiastic boy who sometimes forgets just how big he is, he needs an
experienced big-dog adopter
who can provide confident leadership and continue working with him on his manners and training.

Oggie would do best with
older, dog-savvy kids
who are comfortable around large dogs. A resident dog who enjoys having a big, goofy playmate would be a wonderful bonus!

If you’re ready for a gentle giant who will fill your life with
love, laughs, heavy leans, goofy antics and endless cuddles
, Oggie is ready to meet you. Just bring the chest and belly scratches! ❤️

Oggie is looking for his forever adopter!

Interested in making Oggie part of your family?
Please complete an adoption application online at
LastDayDogs.com
⁠.
Once your application is submitted, the rescue team will review it and follow up with you regarding next steps.

❤️
Apply today and give this big lovable goofball the forever home he deserves!

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Oggie fromTails of the UnwantedGreensboro, NC · listed Jun 27

Rescues and shelters near Mebane

The rescues with the most dogs listed within 50 miles of Mebane.

  • Pawfect Match RescueHolly Springs, NC · 151 dogs · 39 mi from Mebane
  • Franklin County Humane SocietyYoungsville, NC · 69 dogs · 48 mi from Mebane
  • Orange County Animal ServicesChapel Hill, NC · 29 dogs · 14 mi from Mebane
  • Burlington Adoption CenterHaw River, NC · 25 dogs · 4 mi from Mebane
  • Rusty's Rescue Ranchgarner, nc · 22 dogs · 50 mi from Mebane
    How to adopt from Rusty's Rescue Ranch

    An application, a virtual home visit, a vet check and landlord check. Anyone adopting a pet whos other pets will need to do a meet and greet with all animals. Cats are $125, dogs under 6 months of age are $400 and dogs over 6 months of age are $225. an adoption contract is required as well,

  • Perfectly Imperfect PupsRaleigh, NC · 16 dogs · 38 mi from Mebane
    How to adopt from Perfectly Imperfect Pups

    Once we receive your application an adoption counselor will take a look and reach out with any questions. The team will check personal, vet references and check with your landlord if applicable. Your adoption counselor will then set up a time to talk with you and your family (or anyone else involved in the adoption process in your home). This call is a good time to ask any questions you have. Once your application is approved, you will be connected with the foster of the PIP(s) you are interested in. From start to finish, this process can take anywhere from a few days to over a week (so please be patient!). If everything goes well and you and the foster agree that the PIP you want to adopt is a good fit, we will then finalize the adoption. Adoption fees are $325 for adults and $375 for puppies. All dogs will be up to date on age appropriate vaccines and spayed / neutered if old enough. If not old enough adopters can come back to our vet to have it covered in fee. It must be done by the time the dog is 6 months old.

  • Chatham Animal Rescue & EducationPittsboro, NC · 14 dogs · 23 mi from Mebane
    How to adopt from Chatham Animal Rescue & Education

    Adoption application, vet check, reference check, home visit, $100 (cat) or $200 (dog).

  • Carolina Animal Rescue And AdoptionSanford, NC · 12 dogs · 42 mi from Mebane
  • Mitchell Mill Animal Hospital Rescue IncRaleigh, NC · 9 dogs · 44 mi from Mebane
  • Tails of the UnwantedGreensboro, NC · 6 dogs · 34 mi from Mebane
    How to adopt from Tails of the Unwanted

    Application Verify Residence with public records Phone interview Vet Reference Personal Reference Adoptee speaks with foster Meet n Greet/ Home Visit

  • Happy Hills Animal FoundationStaley, NC · 4 dogs · 26 mi from Mebane
  • Best Friend Pet AdoptionCary, NC · 4 dogs · 31 mi from Mebane
    How to adopt from Best Friend Pet Adoption

    All adoptions begin with a trial period of at least 2 weeks before the adoption is finalized. Anyone interested in adopting completes an on line application which must be approved by our adoption coordinator. Process includes reference and vet record checks. All animals must be up to date on all vaccinations, spayed/neutered and microchipped before adoption trial. Fee is $250 for dogs, $115 for cats.

  • Rescue Ur Forever FriendGarner, NC · 4 dogs · 50 mi from Mebane
    How to adopt from Rescue Ur Forever Friend

    Potential adopters meet animal at adoption event or arrangement meeting, Adoption application completed, information verified - vet reference/current animals up to date, home ownership or rental, adoption approved or denied, Adoption fee collected - $150 for dogs, $100 for cats, $100 spay/neuter fee for puppies too young to be altered. Follow-up after adoption at 2 weeks, 1 month, 2 months, 6 months and year. More frequent for unaltered pups.

  • Hart-2-Heart Rescue, Inc.Greensboro, NC · 3 dogs · 31 mi from Mebane
    How to adopt from Hart-2-Heart Rescue, Inc.

    Fees: $500 (includes physical/vaccinations/heartworm test/spay/neuter/dental) Adoption Contract Required: Vet & Reference checks, Home visit, fenced yard and no children under 10 years.

  • Two Paws Up NC Shelter RescueRaleigh, NC · 2 dogs · 41 mi from Mebane
    How to adopt from Two Paws Up NC Shelter Rescue

    Note: All animals have been or will be spayed or neutered prior to adoption. Cats & Kittens Cats and kittens are FeLV/FIV negative (unless otherwise stated), dewormed, treated for fleas and ticks, and are up-to-date on all age-appropriate vaccinations. Dogs & Puppies Dogs and puppies are HW negative, on HW preventative (if 10 weeks of age or older), dewormed, treated for fleas and ticks, and are up-to-date on all age-appropriate vaccinations. Adoption Fees $95 Cats and Kittens $120 Dogs and Puppies $65 Dogs and Cats (if altered prior to entering our program) Adoption Process 1. Fill out our online adoption application. Once we have received your application, we will check the necessary references. If additional information is required, we will contact you. 2. Once approved, arrange a time to meet the animal and foster family. Any questions you may have can be answered at this time. 3. If you decide to move forward with the adoption, you will set up a time to receive your new family member for the seven-day adoption trial period. You will be required to sign an adoption contract and pay the adoption fee at this time. 4. If for any reason during this one-week trial period you feel that the animal is not a perfect match for your family, you can return the animal to 2PawsUp for a full refund. 5. After the one-week trial period is over, the animal is yours to love and cherish forever. 6. If for any reason you are unable to keep the animal, you must return the animal to 2PawsUp. La

Adopting a dog in Mebane

Most rescues ask you to fill in an application, meet the dog, and pay an adoption fee that usually covers spaying or neutering, vaccinations and a microchip. Many are foster-based, so you'll often meet your dog in a volunteer's home rather than a shelter.

Senior dogs are often the calmest companions and the slowest to find homes. If you'd like a settled, affectionate dog, ask the rescues about their older residents.

Puppies go quickly, so if you've fallen for one, contact the rescue soon. Ask how big they're expected to grow, and plan for plenty of house-training and training in the first few months.

Questions about adopting a dog in Mebane

How many dogs are up for adoption in Mebane?

As of November 4, 2026, 372 dogs and puppies are listed for adoption within 50 miles of Mebane, North Carolina, by 17 rescues and shelters. The list is updated every day.

Where can I adopt a dog in Mebane?

The rescues with the most dogs near Mebane right now are Pawfect Match Rescue (Holly Springs, NC), Franklin County Humane Society (Youngsville, NC) and Orange County Animal Services (Chapel Hill, NC). Each dog above has the rescue's phone number and website.

Are there puppies for adoption in Mebane?

Yes. 136 puppys are up for adoption within 50 miles of Mebane.

How do I adopt a dog in Mebane?

Pick a dog and contact the rescue or shelter looking after them. Most ask you to fill in an application, meet the dog, and pay an adoption fee that usually covers spaying or neutering, vaccinations and a microchip.

Listings are updated daily. Rescues are responsible for their own listings; a dog may have been adopted since this page was updated.