Large Dogs for Adoption in Lexington, KY: 30 Big Dogs Looking for a Home
By Dogs of the Day · Updated

Rescues and shelters within 100 miles of Lexington have 49 large dogs up for adoption. Here are the 30 newest, each with photos, their story and how to reach the rescue looking after them.
Big dogs often wait longer for homes than small ones, though many are gentle, loyal and easy-going. Every dog on this page is listed by their rescue as large or extra large, with breeds like Labrador Retriever, German Shepherd and Boxer.
- All dogs 176
- Puppies 54
- Adult Dogs 106
- Senior Dogs 13
- Kid-Friendly Dogs 107
- Cat-Friendly Dogs 95
- Small Dogs 40
Not in Lexington? Find dogs near your zip code.
1. Diesel Doo
Adult · Male · Golden Retriever / Mixed · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- No cats
- House-trained
2. CD Rocky
Puppy · Male · Cane Corso Mastiff / Labrador Retriever / Mixed · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
3. Once Upon a Time
Puppy · Female · Australian Shepherd / Labrador Retriever / Mixed · 76 mi from Lexington



The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
4. Annie O
Adult · Female · Australian Shepherd · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
5. Jack O
Adult · Male · Australian Shepherd · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
6. McRib
Young (1 year) · Male · Unknown breed (short coat) · 71 mi from Lexington










This boy stole everyone’s hearts yesterday! He showed off his tricks at Tractor Supply, was a pro for his bath, played in the yard, and then took a nice long nap.
He headed to the vet and was the perfect gentleman! He got his vaccines and medication for an ear infection, but otherwise received a clean bill of health. He was already neutered, too!
McRib is now safe with his lifesaving foster, Amy, where he’s enjoying the backyard and playing Frisbee. He LOVES people and just wants to be wherever you are!
Read more about McRib
He’s only about a year old, and somewhere along the way, someone took the time to love him, train him, and neuter him. Yet somehow, he ended up a stray and on the euthanasia list.
Please remember, euthanasia doesn't always mean a dog has behavioral or medical issues. They was simply out of space.
He isn't damaged goods. He's a happy, loving pup who deserves a family of his own.
- House-trained
7. Dice
Young · Male · German Shepherd Dog / Mixed · 76 mi from Lexington




Dice is truly the best boy! Rescued from a high-kill shelter, he’s now thriving in his foster home and loving every minute of his second chance. This happy, friendly guy loves everyone he meets—humans big and small, and dogs of all shapes and sizes! He’s always up for an adventure, especially if it involves running through the woods and exploring the great outdoors. Dice is also potty trained, crate trained, and ready to settle right into his forever home. He's the perfect mix of adventure buddy and lovable companion. All he needs now is a family to call his own!If you are interested in meeting and/or adopting this baby, please fill out an application.
Read more about Dice
They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- No cats
8. Charlie Brown Gang
Puppy · Male · Labrador Retriever / Great Pyrenees / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
9. Charlie Brown Gang
Puppy · Male · Labrador Retriever / Great Pyrenees / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
10. Charlie Brown Gang
Puppy · Male · German Shepherd Dog / Great Pyrenees / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
11. Idaho
Puppy · Male · Labrador Retriever / Husky / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
12. Charlie Brown Gang
Puppy · Female · Labrador Retriever / Great Pyrenees / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
13. Charlie Brown Gang
Puppy · Male · German Shepherd Dog / Great Pyrenees / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic . We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
14. Max Love
Adult · Male · Boxer / Mixed · 76 mi from Lexington




Chester is a handsome, athletic boy with a personality as big as his adorable underbite! With his striking white eyelashes and irresistible face, he’s sure to turn heads wherever he goes.This fun-loving guy is a little lightning bolt who enjoys racing around the backyard, chasing squirrels, playing with footballs, and running at the dog park. He’s also a loyal little shadow who loves following his people around the house to see what they’re up to. Affectionate and cuddly, Chester is never shy about squeezing in when someone else is getting attention!Chester enjoys car rides, walks nicely on a harness, and has plenty of personality to keep his family smiling.
Read more about Max Love
He’s a healthy, muscular, active boy who loves adventure just as much as snuggle time.Chester does have some special considerations. He makes bad decisions when left unattended, even when other dogs are present. He will need a patient, committed adopter who will crate him when he cannot be supervised and who understands the importance of training, thoughtful management, and consistency.Chester has so much love to give! He’s looking for an active, understanding family who can provide the companionship, structure, supervision, and support he needs to thrive. With the right guidance and a loving home, this special boy has so much potential to be a wonderful companion. If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
15. Coco Pups
Young · Female · Golden Retriever / Boxer / Mixed · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
16. Owens
Young · Male · German Shepherd Dog / Mixed · 76 mi from Lexington



Forrest is a handsome 8-month-old German Shepherd mix weighing 34 pounds. This sweet boy came into rescue with his sister, Autumn, and is ready to find a family of his own!Forrest gets along great with other dogs and thinks cats might make fun playmates, too! He's still working on his leash manners but is eager to learn.Fully vetted and ready for adoption, Forrest is looking for a loving home where he can continue to grow and thrive! If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
17. Cd
Adult · Female · German Shepherd Dog / Flat-coated Retriever / Mixed · 76 mi from Lexington




Dolly is a 1yr old Labrador Retriever mix. Shee is 60 lbs of fun. She is good with other dogs and ok with cats. Sometimes focuses a bit too much on them. She is house and crate trained. She is food motivated. She is good with children. She knows a few commands.She needs a physical fenceWill go thru an electric fence.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
18. Ra Paws
Adult · Male · Redbone Coonhound / Australian Shepherd / Mixed · 76 mi from Lexington




If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $200 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
19. Georgia
Puppy · Female · Shepherd / Labrador Retriever / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .
- Good with kids
- Good with dogs
- Good with cats
20. Tommy
Adult · Male · Great Pyrenees / Labrador Retriever / Mixed (short coat) · 46 mi from Lexington



Tommy is a foster favorite. He is special needs only because he is getting treatment for heartworms and tick diseases. This should all be resolved in 90 days. Whoever this fella will be getting a gem! Walks well on lead, doesn't pull, gets along with kids and dogs. Please consider foster to adopting this fella while he get healthy again!
This pet is now available for adoption to a good and loving home. If you have a lot of love to share with a best friend please adopt one of our wonderful pets. All pets are fully vetted. Transport is available.
To adopt please complete this online Adoption Form
Feel free to email or call the shelter at 606 768-9368 with any questions or concerns. Thank you for considering a pet in need.
- Good with kids
- Good with dogs
- House-trained
- Special needs
21. Myra
Young · Female · Husky / Mixed (short coat) · 46 mi from Lexington




This very sweeet girl is perfect for a dog that needs a cuddlebug. She walks on lead and doesn't have any issues with other dogs. Great with kids, but not so much with chickens. Very calm for a young husky mix. Consider coming to the shelter to meet Myra.
This pet is now available for adoption to a good and loving home. If you have a lot of love to share with a best friend please adopt one of our wonderful pets. All pets are fully vetted. Transport is available.
To adopt please complete this online Adoption Form
Feel free to email or call the shelter at 606 768-9368 with any questions or concerns. Thank you for considering a pet in need.
- Good with kids
- Good with dogs
22. Bruno Doo
Adult · Male · Labrador Retriever / Boxer / Mixed · 76 mi from Lexington




Bruno is a sweet boy. He is potty trained and good with kids, cats and dogs. He absolutely loves toys. But doesn't like to share his food! If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
- House-trained
23. Nona
Adult · Female · Great Pyrenees / Golden Retriever / Mixed · 76 mi from Lexington



If you are interested in meeting and/or adopting this baby, please fill out an application. They currently are fixed, up to date on shots, wormings, preventatives and are microchipped (with lifetime registration). Adoption fee is $215 with approved application, applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .We cannot guarantee breed or size when full grown.
- Good with kids
- Good with dogs
- Good with cats
24. River Boy
Puppy · Male · Boxer / Shepherd / Mixed · 76 mi from Lexington



Don't miss out on this one. River is 5 months old and 30 lbs. He is a lover boy. He loves playing with friends, going on walks, car rides, hiking, playing in water, and playing in the sandbox. He loves to cuddle and give a few kisses. He is almost house trained. He is crate trained. He is working on leash training and doing wonderfully. The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13).
Read more about River Boy
If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .
- Good with kids
- Good with dogs
- Good with cats
25. Sibbies
Puppy · Female · Boxer / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .
- Good with kids
- Good with dogs
- Good with cats
26. Sibbies
Puppy · Male · Boxer / Mixed · 76 mi from Lexington




The adoption fee for puppies under 6 months of age is $265. If the puppy is too young or small to be fixed there will be a $75 spay/neuter rebate form provided. They currently have at least 1 puppy shot,, flea preventative, heartworm preventative and are microchipped with lifetime registration ($13). If you have serious interest in this puppy, please fill out an application (don't call, email or text before filling out an app or you will have a greater chance of missing out on this puppy). Applications can be filled out at this link. https://www.petstablished.com/adoption_form/10167/generic .
- Good with kids
- Good with dogs
- Good with cats
27. Ace
Adult · Male · Australian Cattle Dog/Blue Heeler / Mixed (medium coat) · 46 mi from Lexington




Ace has been a chained dog his entire life. No comfort, no love. As a result, sometimes he can jump up on you because he is so excited to have people with him. He's a good dog who deserves a loving home. Come and see Ace to find out what a good boy he can be!
This pet is now available for adoption to a good and loving home. If you have a lot of love to share with a best friend please adopt one of our wonderful pets. All pets are fully vetted. Transport is available.
To adopt please complete this online Adoption Form
Feel free to email or call the shelter at 606 768-9368 with any questions or concerns. Thank you for considering a pet in need.
- Good with kids
- Good with dogs
28. Diamond Doll
Young · Female · Labrador Retriever · 91 mi from Lexington




This beautiful chonky girl came from an Amish breeder that was shut down. We initially thought that she was pregnant but she was just overweight! She is happy and gets along well with other dogs. If you would like to meet Diamond, please call ahead. She is in foster care and will need a private viewing arranged. Calling before a long drive is recommended to confirm availability. Ripley County Humane Society, 1202 W County Rd 150 N, Osgood, IN 47037. 812-689-3773 You can fill out an application online at this link - https://petstablished.com/adoption_form/57789/generic .
- Good with kids
- Good with dogs
29. Ryan
Adult · Male · Bulldog / American Staffordshire Terrier / Mixed (short coat) · 46 mi from Lexington



Ryan was found on a rural highway near a campground. He is a sweet, loving boy who gets along with the other dogs at the shelter and who is good with people. He deserves the best home!
This pet is now available for adoption to a good and loving home. If you have a lot of love to share with a best friend please adopt one of our wonderful pets. All pets are fully vetted. Transport is available.
To adopt please complete this online Adoption Form
Feel free to email or call the shelter at 606 768-9368 with any questions or concerns. Thank you for considering a pet in need.
- Good with kids
30. Maggie
Adult · Female · Golden Retriever · 91 mi from Lexington




Meet Maggie! A Golden Girl with a Golden Personality! Looking for a beautiful girl with a heart just as lovely as her looks? Meet Maggie! This gorgeous Goldendoodle is ready to find a home where she can stretch her legs, enjoy life’s little adventures, and be someone’s special girl! Maggie loves getting out into our outdoor pens for a good run! There’s nothing like watching her enjoy the fresh air and stretch those legs. She’s also working on her leash-walking skills and learning more every day! With patience, encouragement, and a little practice, she’s on her way to becoming a wonderful walking companion.
Read more about Maggie
Maggie does not get along with cats or other dogs, so she’ll need to be the only pet in her home. That just means she’ll get all the love, attention, and spoiling from her humans! With her beautiful curly coat and golden personality, Maggie is one special girl who deserves a family of her own. She’s ready for someone who will help her continue learning, enjoy adventures together, and give her a place where she can truly shine. A beautiful Goldendoodle with a golden heart — Maggie is ready to make your life a little brighter! Could you be the one to give this lovely girl her happily-ever-after? If you would like to meet any of our pets, they are available for viewing, every single day from noon until 3:30pm. If you have other dogs a meet and greet is required. Calling before a long drive is recommended to confirm availability. Ripley County Humane Society, 1202 W County Rd 150 N, Osgood, IN 47037. 812-689-3773 You can fill out an application online at this link - https://petstablished.com/adoption_form/57789/generic .
- Only dog
- No cats
Adopting a large dog in Lexington
Large dogs need room to stretch out and plenty of exercise: at least one good walk a day, and a secure yard is a bonus. Check your lease too, as some landlords limit the size or breed of dog.
Start training from day one. A big dog who walks nicely on a leash and doesn't jump up is a pleasure to live with, and many rescues can recommend a local trainer.
Rescues with large dogs near Lexington
- Stray Haven IncAurora, IN · 23 large dogs above
- Menifee County Animal ShelterFrenchburg, KY · 4 large dogs above
- Ripley County Humane SocietyOsgood, IN · 2 large dogs above
- Spoil Em Rotten FoundationCincinnati, OH · 1 large dog above
Questions about adopting large dogs in Lexington
How many large dogs are up for adoption in Lexington?
As of November 4, 2026, rescues and shelters within 100 miles of Lexington, Kentucky, have 49 large dogs up for adoption. The list is updated every day.
Where can I adopt a large dog in Lexington?
The rescues with the most large dogs near Lexington right now are Stray Haven Inc (Aurora, IN), Menifee County Animal Shelter (Frenchburg, KY) and Ripley County Humane Society (Osgood, IN). Each dog above has the rescue's phone number and website.
Can I adopt a large dog if I live in an apartment?
Often, yes. Many big dogs are calm indoors as long as they get enough walks and exercise. Check your lease for size or breed limits, and ask the rescue how active the dog is.
Listings are updated daily. Rescues are responsible for their own listings; a dog may have been adopted since this page was updated.