Durham, NC

Large Dogs for Adoption in Durham, NC: 30 Big Dogs Looking for a Home

Large Dogs up for adoption near Durham, NC

Rescues and shelters within 25 miles of Durham have 40 large dogs up for adoption. Here are the 30 newest, each with photos, their story and how to reach the rescue looking after them.

Big dogs often wait longer for homes than small ones, though many are gentle, loyal and easy-going. Every dog on this page is listed by their rescue as large or extra large, with breeds like Anatolian Shepherd, Coonhound and Labrador Retriever.

1. Bubbles

Puppy (4 months 5 days) · Male · Terrier / Mixed (short coat) · 25 mi from Durham

Hi! I'm new here and a friendly Foster saved me from the shelter. I am so happy to be in a loving home and learning all the puppy things. My foster mom will update here as she learns more about me but I am accepting applications for my future forever family!

________________________________________________________________________

Breed, size & sometimes age is Pawfect Match Rescue's best guess and never guaranteed.

The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age.

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Bubbles fromPawfect Match RescueHolly Springs, NC · listed Nov 3

2. Gloria

Young (3 months 19 days) · Female · German Shepherd Dog / Shepherd / Mixed (medium coat) · 25 mi from Durham

Hey i am gloria ! I was wondering if you could help me out and adopt me. I am the last sibling left to be adopted. I am very sweet and gentle but i also get the zoomies. i am very treat motivated. my mom will meet you ask <

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Gloria fromPawfect Match RescueHolly Springs, NC · listed Oct 23

3. Moe

Puppy (2 months 2 days) · Male · Coonhound / Mixed (short coat) · 25 mi from Durham

Hi! My mom and siblings were rescued by pawfect when we were just born in the shelter. We have been living in a warm cozy foster home and growing, growing, growing! Our mom Brynn (Brinley) is what they think to be a Coonhound mix and we are not sure what our dad was mixed with but likely something big.
We currently live in a foster home with cats, dogs & kids but please remember we are babies and proper introductions and consistent boundaries and training are a must to help me thrive as I grow.
We are accepting applications to be taken home as your new BFF and can't wait to find our forever!

Read more about Moe

The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application!

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Moe fromPawfect Match RescueHolly Springs, NC · listed Oct 21

4. Meeny

Puppy (2 months 2 days) · Female · Coonhound / Mixed (short coat) · 25 mi from Durham

Hi! My mom and siblings were rescued by pawfect when we were just born in the shelter. We have been living in a warm cozy foster home and growing, growing, growing! Our mom Brynn (Brinley) is what they think to be a Coonhound mix and we are not sure what our dad was mixed with but likely something big.
We currently live in a foster home with cats, dogs & kids but please remember we are babies and proper introductions and consistent boundaries and training are a must to help me thrive as I grow.
We are accepting applications to be taken home as your new BFF and can't wait to find our forever!

Read more about Meeny

The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application!

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Meeny fromPawfect Match RescueHolly Springs, NC · listed Oct 21

5. Eeney

Puppy (2 months 2 days) · Male · Coonhound / Mixed (short coat) · 25 mi from Durham

Hi! My mom and siblings were rescued by pawfect when we were just born in the shelter. We have been living in a warm cozy foster home and growing, growing, growing! Our mom Brynn (Brinley) is what they think to be a Coonhound mix and we are not sure what our dad was mixed with but likely something big.
We currently live in a foster home with cats, dogs & kids but please remember we are babies and proper introductions and consistent boundaries and training are a must to help me thrive as I grow.
We are accepting applications to be taken home as your new BFF and can't wait to find our forever!

Read more about Eeney

The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application!

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Eeney fromPawfect Match RescueHolly Springs, NC · listed Oct 21

6. Miney

Puppy (2 months 2 days) · Male · Coonhound / Mixed (short coat) · 25 mi from Durham

Hi! My mom and siblings were rescued by pawfect when we were just born in the shelter. We have been living in a warm cozy foster home and growing, growing, growing! Our mom Brynn (Brinley) is what they think to be a Coonhound mix and we are not sure what our dad was mixed with but likely something big.
We currently live in a foster home with cats, dogs & kids but please remember we are babies and proper introductions and consistent boundaries and training are a must to help me thrive as I grow.
We are accepting applications to be taken home as your new BFF and can't wait to find our forever!

Read more about Miney

The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application!

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Miney fromPawfect Match RescueHolly Springs, NC · listed Oct 21

7. Ash

Puppy (1 month 30 days) · Female · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Ash

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!**************

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
Adopt Ash fromPawfect Match RescueHolly Springs, NC · listed Oct 18

8. Blair

Puppy (1 month 30 days) · Female · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Blair

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!**************

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
Adopt Blair fromPawfect Match RescueHolly Springs, NC · listed Oct 18

9. Ripley

Puppy (1 month 30 days) · Male · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Ripley

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!**************

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
Adopt Ripley fromPawfect Match RescueHolly Springs, NC · listed Oct 18

10. Hunter

Puppy (1 month 30 days) · Male · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Hunter

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!**************

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
Adopt Hunter fromPawfect Match RescueHolly Springs, NC · listed Oct 18

11. Glinda

Puppy (2 months 2 days) · Female · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Glinda

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!**************

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
Adopt Glinda fromPawfect Match RescueHolly Springs, NC · listed Oct 18

12. Chucky

Puppy (2 months 9 days) · Male · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Chucky

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!

  • Good with kids
  • Good with dogs
Adopt Chucky fromPawfect Match RescueHolly Springs, NC · listed Oct 18

13. Burton

Puppy (2 months 4 days) · Male · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Burton

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!

  • Good with kids
  • Good with dogs
Adopt Burton fromPawfect Match RescueHolly Springs, NC · listed Oct 18

14. Carver

Puppy (1 month 30 days) · Male · Anatolian Shepherd / Hound / Mixed (medium coat) · 25 mi from Durham

Meet the Halloween Litter: A Little Spooky, A Whole Lot Sweet!

Our story started with a not-so-magical beginning: we were dumped at just a few weeks old. Thankfully, a kind Good Samaritan came to our rescue, and now our next big adventure is finding forever families!

At just 7 weeks old, we're tiny bundles of puppy breath, wiggly tails, and endless potential. Our breed is still a mystery, but our best guess is a mix of Hound and Anatolian Shepherd. In other words, we might be growing into some BIG dogs with big hearts to match!

Read more about Carver

We may have arrived with a little Halloween drama, but there's nothing scary about us. We're just sweet little pumpkins looking for families to love us, guide us, and help us grow into the amazing dogs we're meant to be.

Ready to make one of us your boo? We promise plenty of puppy kisses, silly antics, and a lifetime of love!

  • Good with kids
  • Good with dogs
Adopt Carver fromPawfect Match RescueHolly Springs, NC · listed Oct 18

15. Joda

Young (4 months 28 days) · Female · Labrador Retriever / Mixed (medium coat) · 25 mi from Durham

I’m Joda, and my name means PARTY in Spanish! So naturally, I’m here to bring the party wherever I go!

I’m a 5-month-old, 24-pound bundle of pure joy, puppy antics, and nonstop entertainment. I’ve got long legs, a shiny black coat, and enough personality to fill a room. I’m basically a walking celebration with four paws!

Life is exciting, everything is worth investigating, and there’s always time for a little silliness. I’m at that perfect puppy age where I’m ready to learn, explore, make memories, and shower my people with all the love I have to give.

Read more about Joda

All I need now is a forever family ready for puppy adventures, plenty of laughs, and a whole lot of love. So, what do you say?

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Joda fromPawfect Match RescueHolly Springs, NC · listed Oct 13

16. Toby

Adult (4 years 11 months) · Male · Labrador Retriever / Terrier / Mixed (short coat) · 25 mi from Durham

Hi! I'm Toby,

Pawfect Match rescued me just before my time ran out at the shelter. I'm a sweet boy now living in a foster home and as they learn more about me my profile will be updated here!

** The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Toby fromPawfect Match RescueHolly Springs, NC · listed Oct 12

17. Sampson

Puppy (4 months 6 days) · Male · Great Pyrenees (long coat) · 25 mi from Durham

A good samaritan learned about me living outside tied up by a chain and rescued me from those conditions. He knew he would not be able to keep me but also knew he couldn't leave me where I was. He took me to the vet, got me meds for my ear infection and got me all cleaned up. I'm now in a foster home with Pawfect Match and will learn how to be a puppy. I have a sweet, calm demeanor and have done well with dogs, kids and people although I'm a little shy at the moment.
I will need a home with a yard as I will be a big boy as I grow older. I will shed, require brushing and wil need someone who understands my breed.

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Sampson fromPawfect Match RescueHolly Springs, NC · listed Oct 6

18. Chip

Adult (5 years) · Male · German Shepherd Dog / Hound / Mixed (short coat) · 25 mi from Durham

Are you looking for a professional couch potato? How about a dog that basically sleeps on demand? Want a dog to pre-warm your bed before you get in? Look no further! Chip, AKA The House Hippo is DEFINITELY the dog for you.

Housetrained? Check.
Young at 5 years old, but with all that puppy stuff in the past? Check.
Good on a leash? Check.
Great with other dogs? Kids? Check, check.
Healthy? UTD on veterinary care? Neutered? Also check.

Read more about Chip

This dude is the total derpy package. He is sweet, gentle, and thinks his name should be Tiny, since he also believes he is a lap dog and will absolutely block your view of the TV if he joins you on the couch. But it is totally worth it, since he has an enormous amount of love to give. He was saved from euthanasia at a rural shelter with just hours to spare. And he is forever grateful and will for sure let it show. Chip would absolutely 100% benefit from being in a home with other dogs! We don’t think he would flourish as only dog!

Won't you consider adding this hunk of love to your pack?

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Chip fromPawfect Match RescueHolly Springs, NC · listed Sep 29

19. Coda

Adult (2 years) · Male · American Pit Bull Terrier (short coat) · 25 mi from Durham

Meet Coda!

Coda was pulled from the shelter and spent time in boarding while being observed and trained! This boy has GREAT manners and such a great foundation for training!

A message from his trainer:

He's doing really well. Hes a different dog from the one I brought into the shelter.

Polite on a leash, knows basic obedience, understands dog manners well (still ignores them sometimes), and hes become way more social with people.

He'll still barks at someone that comes in the house initially or unexpectedly but is learning he's safe and with proper introductions warms up.

****************

Read more about Coda

The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Coda fromPawfect Match RescueHolly Springs, NC · listed Sep 29

20. Nessa

Puppy (5 months 18 days) · Female · Labrador Retriever / Giant Schnauzer / Mixed (medium coat) · 23 mi from Durham

Meet Nessa! We think she could be a mix of Lab or Great Dane and some sort of wiry-haired terrier, but whatever she is, her paws tell us she's going to be a great big beautiful girl. Good thing she's such a sweetheart who loves to learn. Nessa requests your treats and chin scratches and she can provide giant cuddles as payment!

Read more about Nessa

In her foster home, she's house trained, knows some basic commands like sit/down, and takes treats gently. She's learning to walk politely on a leash and sleeps well in her crate at night. She loves to chase the ball, but she hasn't yet gotten the hang of bringing it back. During the day, she's still learning that her crate can be her safe place because she loves to be with people. Having another dog in the home could help her feel more confident when her people leave the house.

Nessa is current on vaccines and microchipped.

  • Good with dogs
  • House-trained
Adopt Nessa fromChatham Animal Rescue & EducationPittsboro, NC · listed Sep 28

21. Morpheus

Senior · Male · Labrador Retriever / Mixed · 19 mi from Durham

Do you need a buddy? A buddy for you? A buddy for your dog? A buddy for your older kiddo? This guy is the best at being a buddy! Morpheus is not only handsome, he's cuddly and adorable. He would love to hang out next to you on the couch, sleep with you in the bed (stairs please, if your bed is kinda high), and just be near. He loves belly rubs and snuggles and chin chucks. He rides great in the car, and he's pretty good on leash as well. He's house trained and is crate trained, but has free roam of his current foster home, along with his three foster brothers. He lives a quiet life with low key dogs, but every once in a while he'll get goofy and start rolling around on the floor like a big dork, making all kinds of happy sounds.

Read more about Morpheus

When he's displeased, he'll yodel a little, full disclosure. But it's not long-lived. He just wants to be around his people. So if you're looking for the easiest guy to have around, Morpheus is that guy. He might be a senior, but he's still got a lot of life and love to give. Adoption fee of $90 includes neuter, microchip, vaccines, deworming, heartworm testing, and heartworm/flea/tick preventionApply here: https://2pawsup.org/applications/adoption-application/

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Morpheus fromTwo Paws Up NC Shelter RescueRaleigh, NC · listed Sep 27

22. Bonita

Young (1 year 8 months) · Female · Great Pyrenees / Hound / Mixed (short coat) · 25 mi from Durham

Hi I'm Bonita,

My puppies and I were saved by Pawfect Match just before our time was up! I am in a loving foster home with fur siblings and am doing really well. I still feel a little nervous and timid around humans but I love walking with and playing with my fur siblings.

I'm looking for my own forever home so please apply or ask to meet me at one of our upcoming events!

Read more about Bonita

****** The adoption fee is $400. All dogs receive a wellness visit, vaccines, heartworm test, flea, tick and heartworm preventative, deworming, spay/neuter surgery, and a microchip as appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Bonita fromPawfect Match RescueHolly Springs, NC · listed Sep 14

23. Peaches

Puppy (3 months 19 days) · Female · Doberman Pinscher / Great Pyrenees / Mixed (short coat) · 25 mi from Durham

Hi,

I'm Peaches!

My brother and sisters and I were saved right in the nick of time with our mom when we found ourselves at the shelter. Us puppies had a sickness called parvo but Pawfect match acted quick and got us treated. We are now feeling better than ever and are happy to be thriving.

We are working on learning how to be a normal fun puppy and being loved on in our foster homes but would love to find our forever families to settle in our final spot.

Read more about Peaches

Our mom is pictured in our photos and guess what?? One of my sibling had a DNA test and the results showed 50% Doberman Pinscher, 26.6% Great Pyrenees, 14.3% Super mutt and 9.1% Belgian Malinois. It is possible that my siblings and I could have different Dads so even a sibling DNA is no guarantee.

I hope to meet you soon at one of our upcoming events!

****** The adoption fee is $400. All dogs receive a wellness visit, vaccines, heartworm test, flea, tick and heartworm preventative, deworming, spay/neuter surgery, and a microchip as appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application

  • Good with kids
  • Good with dogs
  • Good with cats
Adopt Peaches fromPawfect Match RescueHolly Springs, NC · listed Sep 14

24. Benny

Young (11 months) · Male · Shepherd / Mixed (medium coat) · 25 mi from Durham

Benny’s story almost ended before it truly had a chance to begin. This sweet boy was sitting in a Georgia shelter and was scheduled to be euthanized that very day. With only hours left, he was pulled to safety—and now, thanks to Pawfect Match Rescue, Benny has a second chance to find the family he deserves. Benny is an approximately 9-month-old German Shepherd mix with all the fun, goofy energy you’d expect from a puppy! He loves to play, enjoys chewing on his bones, and when he’s finally worn himself out, he is more than happy to settle in for a good nap. And this smart boy already has some important skills under his belt! Benny is potty trained and crate trained.

Read more about Benny

He is also very food motivated, which can be a huge help as he continues learning and training. Benny is still young, and he does have more to learn. He needs a family who understands that becoming the best dog he can be takes patience, consistency, guidance, and love. Give this boy the chance to learn what’s expected of him, and he has so much potential to absolutely thrive. He came within hours of losing his life. Now he’s just waiting for someone to show him what forever feels like.

  • Good with kids
  • Only dog
  • No cats
  • House-trained
Adopt Benny fromPawfect Match RescueHolly Springs, NC · listed Sep 7

25. Freddie

Puppy (5 months 3 days) · Female · American Pit Bull Terrier / Mixed (short coat) · 25 mi from Durham

Hi future family! My name is Freddie, and I can't wait to meet you! I'm a chill girl, because while I do like to play, I also enjoy finding a soft place to snuggle up and take a nap. When it is time to play, I love to play tug of war or chew a squeaky toy. Exploring the yard is fun too! I can be shy when I meet new people, but my family is extremely important to me. A chew toy or a kong with a treat is a favorite for me, and if you're nearby, I'll take a nap peacefully for a few hours. If you have to leave the house, I'm happy to wait for you in my crate. I'm on a good potty schedule, and as long as I keep that schedule, I am housetrained! At night I am used to sleeping in my crate, but if you wanted me to snuggle up on your bed with you, I would absolutely love that! I hope I get to meet you soon!

Read more about Freddie

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The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Freddie fromPawfect Match RescueHolly Springs, NC · listed Aug 25

26. Willow

Puppy · Female · American Pit Bull Terrier / Mixed · 16 mi from Durham

Meet Willow!Willow is a 7 month old bundle of joy with the sweetest personality and the most adorable curious spirit. She is playful, affectionate, and incredibly smart, always eager to learn something new, especially if treats are involved. This bright little girl truly loves people & other dogs and thrives on connection. She would be happiest in a home where she has plenty of companionship, whether that is a human best friend, a playful dog sibling, or both.Willow absolutely adores other dogs and lights up anytime she sees one. She is very social and always initiates play, greeting other pups with gentle, submissive rolls that make her easy to love.

Read more about Willow

She has also spent time with many children and has done wonderfully, making her a great fit for a family environment.She enjoys exploring the yard, chasing toys, and then coming back for snuggles and attention. Willow loves her toys and will happily entertain herself or join in on playtime. She loves going for walks and she is eager to please and very food motivated, which makes her a fantastic candidate for training and continued learning.Willow is currently doing great learning basic commands and she is fully crate trained! She does great with bath time and will even let you brush her teeth & trim her nails! She’s so smart and really wants to impress you!With her loving nature, playful spirit, and bright mind, Willow is the kind of pup who will grow into an amazing lifelong companion. If you are looking for a sweet, social, and smart puppy to grow with your family, Willow might just be your perfect match.Thank you to Hatteras of Oakway Townes for sponsoring $150 of Willow's adoption fee!

  • Good with kids
  • Good with dogs
Adopt Willow fromPerfectly Imperfect PupsRaleigh, NC · listed Aug 24

27. Cobbler

Adult (5 years 1 month) · Female · English Coonhound / Mixed (short coat) · 21 mi from Durham

There's nothing quite like a warm Cobbler... and this one is guaranteed to leave you smiling.

Just like the dessert, Cobbler is full of comfort, sweetness, and all the good things that make you feel at home. She's got the perfect recipe: a generous scoop of goofy, a heaping helping of love, and just enough hound curiosity to keep life interesting.

Read more about Cobbler

This beautiful 5-year-old red-and-white hound girl is always ready to dish out affection, serve up a good time, and make friends wherever she goes. Whether she's hanging out with people or playing with other dogs, Cobbler fits right in. We'd say she's the cherry on top, but honestly, she's the whole dessert.

Cobbler is spayed, up to date on vaccines, on heartworm prevention, and ready to find a family to bring her out of the oven and into a forever home. One meeting with this sweet girl, and you'll be coming back for seconds. Miss Cobbler is positive for heartworms, but receiving treatment.

  • Good with kids
  • Good with dogs
Adopt Cobbler fromMitchell Mill Animal Hospital Rescue IncRaleigh, NC · listed Aug 6

28. Blue

Young (1 year 3 months) · Male · American Pit Bull Terrier / Terrier / Mixed (short coat) · 25 mi from Durham

Blue was rescued by Pawfect Match just in time before the deadline thanks to a wonderful foster who stepped up to keep him safe. He has been dog friendly with the dogs he has met and has not been cat reactive but hasn't been officially cat tested.

Foster Update!

Blue is super high energy and wants to play all the time!

He is good with my small dog but constantly tries to get him to play.

I don’t have a cat but every time he sees one he tries to chase it so I’m not sure how he would do in a house with one.

Read more about Blue

He is a social butterfly and loves company of any kind; that being said he does not like being alone.He has gotten a bit better, but when I first left him alone he would destroy everything so consistent positive routines and reassurance is a must with this boy!

He is pretty much house trained at this point, we hardly have any accidents in the house anymore.

He would do well with an active, younger person or family. He walks well on a leash, but I would suggest using a harness. He knows how to escape the collar pretty well.

We will be neutering, vetting and gettin to know Blue and will update as we can!

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The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application.

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Blue fromPawfect Match RescueHolly Springs, NC · listed Aug 5

29. Jazz

Puppy · Female · Foxhound / English Bulldog / Mixed · 16 mi from Durham

This pup is eligible for our Test the Couch program — a 7-day trial adoption to see if your home (and your couch) is the perfect fit. Learn more https://pipsrescue.org/test-the-couch/Meet Jazz – your future backyard explorer, chase champion, and certified cuddle bug! While she’s not quite a swimmer (she’s more of a "dip a paw in and call it good" kind of gal), Jazz is all about the adventures in the fenced-in yard, sniffing out every blade of grass and investigating all things fun. If you’ve got a playmate for her, she’s ready to unleash her zoomies and show off her chase skills – she’s got the fastest paws in the game.Jazz is sweet, loves all the attention, and will definitely work her way into your heart with her charm and snuggles.

Read more about Jazz

Food-motivated and eager to please, she learns quickly – so training is a breeze if you’ve got treats on hand. She’s crate trained and housetrained (she knows where the bathroom is, no need for a tour), but honestly, she’d rather skip the crate and curl up next to you for a good snuggle session.Bonus points if you’ve got a fellow pup to keep her company. Jazz would love a playmate to share her backyard adventures and zoomies with. So if you're looking for a sweet, playful, and cuddly companion, Jazz is your girl!

  • Good with kids
  • Good with dogs
  • House-trained
Adopt Jazz fromPerfectly Imperfect PupsRaleigh, NC · listed Jul 25

30. Haven

Adult (5 years) · Female · American Staffordshire Terrier / Labrador Retriever / Mixed (short coat) · 25 mi from Durham

Haven was rescued from Rowan county shelter! She is a very sweet girl. She does well with dogs and cats! She is shy with people and nervous with strangers at first but she’s doing better each week and once she warms up she is your pal! She lives in a home currently with a cat! Haven is house trained and crate trained, she does not potty inside and is sound in her crate when she’s in it.
She is a wonderful dog and walks good on leash too, she would make anyone a great companion!

  • Good with kids
  • Good with dogs
  • Good with cats
  • House-trained
Adopt Haven fromPawfect Match RescueHolly Springs, NC · listed Jul 22

Adopting a large dog in Durham

Large dogs need room to stretch out and plenty of exercise: at least one good walk a day, and a secure yard is a bonus. Check your lease too, as some landlords limit the size or breed of dog.

Start training from day one. A big dog who walks nicely on a leash and doesn't jump up is a pleasure to live with, and many rescues can recommend a local trainer.

Rescues with large dogs near Durham

Questions about adopting large dogs in Durham

How many large dogs are up for adoption in Durham?

As of November 4, 2026, rescues and shelters within 25 miles of Durham, North Carolina, have 40 large dogs up for adoption. The list is updated every day.

Where can I adopt a large dog in Durham?

The rescues with the most large dogs near Durham right now are Pawfect Match Rescue (Holly Springs, NC), Perfectly Imperfect Pups (Raleigh, NC) and Chatham Animal Rescue & Education (Pittsboro, NC). Each dog above has the rescue's phone number and website.

Can I adopt a large dog if I live in an apartment?

Often, yes. Many big dogs are calm indoors as long as they get enough walks and exercise. Check your lease for size or breed limits, and ask the rescue how active the dog is.

Listings are updated daily. Rescues are responsible for their own listings; a dog may have been adopted since this page was updated.