Large Dogs for Adoption in Syracuse, NY: 15 Big Dogs Looking for a Home
By Dogs of the Day · Updated

Rescues and shelters within 100 miles of Syracuse have 15 large dogs up for adoption. Here are all 15, each with photos, their story and how to reach the rescue looking after them.
Big dogs often wait longer for homes than small ones, though many are gentle, loyal and easy-going. Every dog on this page is listed by their rescue as large or extra large, with breeds like Labrador Retriever, Shepherd and Terrier.
Not in Syracuse? Find dogs near your zip code.
1. Myrtle
Adult · Female · Labrador Retriever · 5 mi from Syracuse




Sweet senior alert! Myrtle is here, and she’s looking for a soft place to land! More information coming soon. In the meantime, for questions or to set up a meet & greet, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or stop in Monday through Saturday 12 through 4:30; or you can begin the adoption process for Myrtle right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
2. Chance
Young · Male · Boxer · 5 mi from Syracuse




Introducing Chance!Chance is one handsome 1-year-old boy weighing 51 lbs. and believed to be a Boxer mix.He’s brand new to us (as of late October), but here’s what we’ve learned so far:— Loves other dogs!— Has the sweetest personality!— A young enthusiastic boy ready for adventures!We’ll add updates, but we love seeing our dogs get in and out of the shelter quickly, and we are hoping Chance goes home sooner rather than later! Could Chance be the perfect addition to your family? Come meet him and see for yourself! To set up a meet & greet, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or stop in Monday through Saturday 12 through 4:30; or you can begin the adoption process for Chance right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with dogs
3. Big Al
Adult (6 years 2 months) · Male · Poodle (Standard) · 74 mi from Syracuse




Meet Big Al!
The 65-Pound Best Friend You Didn't Know You Needed!
Born August 12, 2020, Al is a 6-year-old Standard Poodle with a BIG heart of gold. And we mean BIG! This handsome guy is currently 65 pounds of lean poodle perfection and is working on putting on a little weight.
Al has never met a stranger. In fact, we're not entirely sure he understands the concept of personal space.
Everyone is his friend. EVERYONE.
The dog snarling at him from across the room? Friend!
The cat who's hissed at him 20 times and finally resorted to throwing paws? Still a friend!
The squirrel across the road? BEST FRIEND MATERIAL!
Read more about Big Al
Al is socially blind and unintentionally pushy. He takes friendship VERY seriously and believes that if he looks at you, you are now personally responsible for being his buddy until someone else comes along. Pets, attention, and affection are always on his agenda! Be prepared, he’s a BIG leaner
A little more about Al:
Dog friendly, including small dogs
Cat friendly
Kid friendly
Potty trained
Kennel trained
Ball enthusiast…when the spirit moves him
Gentle with his toys (more of a casual nibbler than a destroyer)
Low-energy overall and an oversized lapdog at heart
Loves attention and affection
Currently does great with professional grooming
Bed HOG
Al does have a few quirks and things his future family should know:
He's a bit of a puller on walks and will need a head halter or martingale collar while you continue working on that
He's an alert barker, especially at loud noises or people passing his gate. He'd really like them to come over and pet him, obviously!
Counter surfing is one of his hobbies. Keep those snacks out of reach!
He may occasionally bounce around and attempt to initiate a game of tag with a squirrel. The squirrel is generally not interested.
Let's talk Poodle maintenance!
Al is a Standard Poodle, and that gorgeous coat doesn't maintain itself. His hair grows FAST, and he will need professional grooming approximately every month to keep his coat clean, healthy, and mat-free, along with regular nail care.
He currently does wonderfully with professional grooming, so haircuts and nail trims aren't an issue for him. However, his future family needs to be prepared to either learn to groom him at home or budget approximately $80–$200 per month for professional grooming.
If you're looking for a sweet, goofy, affectionate companion who believes everyone he meets should immediately become part of his social circle, Al might just be your guy!
Filling an application is the first step to meet him! -
www.RochesterRASCALS.org/dogs
- Good with kids
- Good with dogs
- Good with cats
- House-trained
4. Cole
Young · Male · Shepherd / Mixed · 5 mi from Syracuse




Introducing Cole — A Little Mystery, a Lot to Love!We’re not exactly sure what breeds went into making Cole, but whatever the mix, the result is one handsome guy complete with nicely situated spotted and brindle markings on his mostly black coat. Cole is a bigger guy, on the border of medium and large, with a wonderfully gentle approach to life. Pulling on the leash? Not his style! He prefers to take his time, exploring, sniffing, and ambling along, with frequent check-ins to make sure his human is still enjoying the stroll.He’s curious about dogs he passes but remains friendly and relaxed.
Read more about Cole
He loves people, enjoys playing with other dogs, and is simply a pleasure to spend time with.If you’re looking for an affectionate, easygoing companion who knows how to enjoy life’s little pleasures, Cole might be your perfect match! To set up a meet & greet, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or stop in Monday through Saturday 12 through 4:30; or you can begin the adoption process for Cole right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with dogs
5. Jason
Young · Male · Terrier / Mixed · 5 mi from Syracuse




Introducing Jason — A Sweetheart with a Hunter’s Heart!Handsome Jason is a sweet, young, medium-sized hound with a lovable personality and a nose that knows a thing or two about adventure. The majority of the time, Jason is a pleasant walking companion who doesn’t pull on the leash; but let him catch an interesting scent or spot a woodland critter, and suddenly his inner hunting dog spirit springs to life! His excitement is contagious, and he may do a little bouncing and dancing as he dreams of giving chase. Fortunately, his smaller size makes him quite manageable.Jason is especially animated when he’s near the road, so he’ll appreciate a watchful handler who can help him navigate all that excitement safely.With his handsome hound looks, sweet disposition, and enthusiastic curiosity about the world, Jason is a delightful character just waiting for someone to share his adventures.
Read more about Jason
Could this charming hound be your new best friend? To set up a meet & greet, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or stop in Monday through Saturday 12 through 4:30; or you can begin the adoption process for Jason right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Only dog
- House-trained
6. Gigi
Young · Female · Pit Bull Terrier · 5 mi from Syracuse




Gigi is a sweet, young pit mix, on the small side (38 lbs). She is loads of fun and loves other dogs. She will be the life of the party! More information coming soon. In the meantime, for questions or to set up a meet & greet, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or stop in Monday through Saturday 12 through 4:30; or you can begin the adoption process for Gigi right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with dogs
7. Ryan
Senior · Male · Husky / Labrador Retriever / Mixed · 86 mi from Syracuse


Ryan is a silly, goofy 70 pound husky mix boy who is about 9 years old. He loves people and playing with some other dogs! He is talkative, playful and full of life.Ryan needs an adult home to retire in. ♥
- No cats
- House-trained
8. Cupid
Young (1 year 8 months) · Male · German Shepherd Dog (medium coat) · 74 mi from Syracuse




Meet 1½-year-old Cupid!
Like many shepherds, Cupid takes a moment to warm up to new people—but once you're in his circle, you'll have a fiercely loyal best friend for life.
Cupid is:
House trained
Crate trained
Dog friendly (he does best with medium/large dogs—his play style is a little too enthusiastic for small pups!)
Young, playful, and ready for adventure
Cupid is looking for:
A home without children, as they make him a bit nervous
A large fenced yard or acreage where he can stretch his legs
A hiking partner, explorer, and best friend who understands the breed and will give him the time he needs to settle in and thrive
Read more about Cupid
This sweet boy has so much love to give.
Could you be Cupid's forever person?
Cupid's adoption fee is $400
Filling an application is the first step to meet him! -
www.RochesterRASCALS.org/dogs
- No young kids
- Good with dogs
- House-trained
9. Gummy Bear
Adult · Male · Labrador Retriever / Mixed · 5 mi from Syracuse




Gummy Bear is sweet, affectionate, and just a little shy, but so ready to meet you! More info coming soon, but in the meantime you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org to set up a meet & greet; or you can begin the adoption process for him right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
10. Jeremy
Senior · Male · Labrador Retriever / Mixed · 5 mi from Syracuse


Calling all senior dog lovers! Jeremy is ready to settle in to his forever home with a reliable, loving person/couple/family. More info coming soon, but in the meantime you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org to set up a meet & greet; or you can begin the adoption process for him right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
11. Asha Oriskany Falls NY
Puppy (4 months 6 days) · Female · Pointer / Labrador Retriever / Mixed · 43 mi from Syracuse



Interested in this dog?
Your new pet is fostered in Smyrna, NY - Contact Sarah (call or text) at 908-745-9191 or you can email her at sarah@eastcoastadoptions.com. You can also fill out an application for this dog at http://eastcoastadoptions.com
We are a registered 501(c)3 Non Profit Organization - A Dogs In Danger Rescue, Inc. company.
Read more about Asha Oriskany Falls NY
Our dogs and puppies are rescued from shelters and rescues in overpopulated areas of the country and are now available for adoption!
All are up to date on vaccines, vet checked, health certified and dewormed.
Hours: Please only call between the hours of 8:30am-8:30pm to come see our dogs looking for homes. Appointments are 7 days a week and most holidays as long as someone is available to see you. If you get voicemail, please leave a message and we will get back to you as soon as we can!
Many of our locations offer crates, playpens and starter kits (leash, collar, food, toys, treats, bowl etc) for a donation.
We do same day adoptions. An application is required before coming to visit our adoptable dogs.
We are committed to saving dogs and puppies in need, finding them loving homes, and offering support and education to ensure a successful forever solution for both our dogs and the humans who adopt them.
You can find additional information and all of our adoptable dogs listed on our website: http://eastcoastadoptions.com - where you can also fill out an application, find out more about us including our fosters or, simply drop us a line for more information! We look forward to hearing from you and completing your family with another family member!
Eastcoastadoptions.com
- Good with kids
- Good with dogs
- Good with cats
12. Remi Blue
Young · Male · Pit Bull Terrier · 91 mi from Syracuse




Meet Remi! This handsome, almost 2-year-old Pittie mix is a fun-loving, playful guy who loves making new human friends. Remi absolutely loves his butt rubs and toys, and he’d love nothing more than to spend his time with his humans. Remi walks well on leash and is very smart. He’d love a family that keeps both his body and mind active. Plenty of opportunities to learn, explore, and play will help Remi be his happiest self. Remi may need some time to warm up when meeting a new dog, but once he’s comfortable, he loves showing off his zoomies and wrestling skills. Remi will need a properly matched dog in the home.
Read more about Remi Blue
We hope to learn more about his compatibility with other dogs as he settles in and will update his profile as we do! If you’re looking for a goofy, affectionate companion with plenty of personality, Remi Blue may just be your guy!Current Weight: 56lbsAdoption Fee: $250To apply: fcrspca.org/adopt
13. Nanook
Senior · Male · Labrador Retriever / Husky / Mixed · 5 mi from Syracuse




From Nanook’s current foster family:Nanook is a 9-year-old husky/shepherd/lab mix VERY deserving of a loving retirement home and comfy couch. He has come into our home from an uncertain past but has proven to be sweet and calm. His eye area is still healing from a previous injury. He walks great on a leash and rides well in a car.We started him in a kennel when we weren't home, but we quickly realized he wasn't going to destroy anything so once he settles in he is safe to be trusted out of a kennel.He is great with his foster brother, they mostly ignore each other. Like a true sibling he just wants equal attention.
Read more about Nanook
He sometimes gets excited when he meets other dogs or takes a minute to warm up. We've seen no food aggression at feeding times. Nanook is very good with our child — gentle and loves to cuddle on her. We have seen no bad triggers with any kind of a person for him. Needs a home that understands husky behavior and noises, such as the-old-man-grumbles and the cute mini-howls when he wants something. Will need long-term medicine for his eye and anal fissures. Takes pills and receives eye drops without any problems. He is a perfect blend of an old man dog with bouts of a happy and playful soul!To set up a meet & greet or ask questions about Nanook, you can contact HumaneCNY at (315) 457-8762 or info@humanecny.org; or you can begin the adoption process for this great dog right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with kids
- Good with dogs
- House-trained
14. Petey
Adult · Male · Terrier / Mixed · 5 mi from Syracuse




Introducing Petey!Dark and handsome, Petey is the kind of dog who quietly works his way into your heart.When you first meet him, he may hang back for a few minutes. Petey is a shy boy who needs a little time to feel safe, and he is more hesitant around men than women; but once he realizes you're kind, you can see the sweet dog underneath beginning to shine. He loves affection and will happily lean right into you while you offer it. Petey is already showing us what a good boy he is. He hasn't minded being around other dogs or cats, and each day we're helping him build the confidence he deserves.
Read more about Petey
We know that with a patient adopter, a little encouragement, and lots of love, Petey is going to blossom. Here at HumaneCNY he has been enjoying spending time his new buddy Tigger. We can see from this relationship that he would thrive in a home where he has canine companionship. If you've ever watched a shy dog learn to trust, you know just how rewarding that journey can be. Petey is ready for someone willing to take that journey with him. You can begin the adoption process for him right now by filling out an application on our website, www.humanecny.org; or email info@humanecny.org; or call us at (315) 457-8762.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with dogs
15. Jasper
Adult · Male · Shepherd / Mixed · 5 mi from Syracuse



Looking for a four-legged adventure buddy? Meet Jasper!This handsome shepherd mix is smart, affectionate, and always ready to get out and explore. Whether you're heading to your favorite hiking trail, taking a long walk, or simply enjoying the outdoors, Jasper will be happiest right there with you.He enjoys the company of other dogs, but he doesn't need a canine companion to be happy. What Jasper really wants is a person or family to share life's adventures with. With his loyal heart, sharp mind, and active personality, he's ready to be someone's very best friend. To schedule a meet and greet with Jasper, call (315) 457-8762 or email info@humanecny.org; or you can begin the adoption process for this great dog right now by filling out an application on our website, www.humanecny.org.Contact HumaneCNY if interested in this animal. You can fill out application to adopt at the shelter.
- Good with dogs
Adopting a large dog in Syracuse
Large dogs need room to stretch out and plenty of exercise: at least one good walk a day, and a secure yard is a bonus. Check your lease too, as some landlords limit the size or breed of dog.
Start training from day one. A big dog who walks nicely on a leash and doesn't jump up is a pleasure to live with, and many rescues can recommend a local trainer.
Rescues with large dogs near Syracuse
- Humane Association of CNYLiverpool, Ny · 10 large dogs above
- Rochester Rascals Pet Rescue IncRochester, NY · 2 large dogs above
- Ayres Memorial Animal Shelter, Inc133 Hilltop Rd Sprakers NY 12166, NY · 1 large dog above
- East Coast Adoption AgencySherburne, NY · 1 large dog above
- Regional SPCAGloversville, NY · 1 large dog above
Questions about adopting large dogs in Syracuse
How many large dogs are up for adoption in Syracuse?
As of November 4, 2026, rescues and shelters within 100 miles of Syracuse, New York, have 15 large dogs up for adoption. The list is updated every day.
Where can I adopt a large dog in Syracuse?
The rescues with the most large dogs near Syracuse right now are Humane Association of CNY (Liverpool, Ny), Rochester Rascals Pet Rescue Inc (Rochester, NY) and Ayres Memorial Animal Shelter, Inc (133 Hilltop Rd Sprakers NY 12166, NY). Each dog above has the rescue's phone number and website.
Can I adopt a large dog if I live in an apartment?
Often, yes. Many big dogs are calm indoors as long as they get enough walks and exercise. Check your lease for size or breed limits, and ask the rescue how active the dog is.
Listings are updated daily. Rescues are responsible for their own listings; a dog may have been adopted since this page was updated.